On April 10, 1963, the USS Thresher (SSN 593) sank during deep-diving tests about 220 miles (350 km) east of Boston, Massachusetts, killing all 129 crew and shipyard personnel aboard. Her loss was a watershed for the U.S. Navy, leading to the implementation of a rigorous submarine safety program known as SUBSAFE. The first nuclear submarine lost at sea, Thresher was also the first of only two submarines that killed more than 100 people aboard; the other was the Russian Kursk, which sank with 118 aboard in 2000.